One of the mysteries of the English language finally explained.
1‘it has nothing to do with your enquiries’
be unconnected with, be unrelated to
be irrelevant to, be extraneous to, be inapplicable to, be inapposite to, be extrinsic to
rare be malapropos of
2‘he's a hard, ruthless man and I'll have nothing to do with him’
avoid, have no dealings with, have no truck with, avoid dealing with, have no contact with, steer clear of, give a wide berth to
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