Definition of vesicate in US English:

vesicate

verb

[with object]Medicine
  • 1Raise blisters on.

    • ‘Both the root in substance, and the juice, have a disagreeable smell, and a nauseous, bitter biting taste: applied for some time to the skin, they inflame or even vesicate the part.’
    • ‘The plant reddens and vesicates healthy skin and has been used as a counter-irritant.’
    • ‘The patient should remain perfectly quiet during the time it is on, lest any motion should bring the blister against the scrotum, and vesicate it.’
    1. 1.1no object Form blisters.

Origin

Mid 17th century: from late Latin vesicat- ‘having pustules’, from vesica ‘bladder’.

Pronunciation

vesicate

/ˈvesəˌkāt//ˈvɛsəˌkeɪt/