Definition of variant CJD in US English:

variant CJD


  • (In full "variant Creutzfeldt-Jakob disease") a form of spongiform encephalopathy distinguished from typical (sporadic) Creutzfeldt–Jakob disease by earlier age of onset, early psychiatric and sensory symptoms, and certain neuropathological features (especially prominent prion protein plaques), and thought to be causally linked with bovine spongiform encephalopathy (BSE); abbreviated vCJD.


1990s; earliest use found in Proceedings of the National Academy of Sciences of the United States of America.