One of the mysteries of the English language finally explained.
(of an immature or stem cell) capable of giving rise to any cell type or (of a blastomere) a complete embryo.
- ‘Here, human or mouse embryonic stem cells, in vitro representatives of the totipotent inner cell mass blastomeres, are placed into culture.’
- ‘In the early stages after fertilization - immediately after a sperm and egg join together and begin dividing - stem cells are considered totipotent.’
- ‘What he showed next were a series of experiments in which they pushed cultured, totipotent mouse embryonic stem cells to desired neural fates using the various factors he had identified as significant in vivo.’
- ‘For the first few divisions, up to at least the 8-cell stage, all the cells of the tiny embryo are totipotent stem cells.’
- ‘Thus, unlike totipotent single-cell embryos, pluripotent embryonic stem cells are specialized cells that have limited developmental capabilities.’
Early 20th century: from Latin totus ‘whole’ + potent.
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