Definition of thymidine in US English:



  • A crystalline nucleoside present in DNA, consisting of thymine linked to deoxyribose.

    • ‘However, as indicated above, the salvage pathway to thymidine nucleotide synthesis is especially important in the preparation for cell division.’
    • ‘A DNA substrate containing a thymidine kinase gene fused to a neomycin-resistance gene was stably integrated into cells.’
    • ‘Methionine synthase inhibition causes folate trapping and a reduction in the amount of folate available for thymidine synthesis as described above.’
    • ‘For gene therapy based on the introduction of the herpes simplex virus thymidine kinase gene, the bystander effect depends on cell to cell contact and the presence of gap junctions.’
    • ‘Both of these enzymes are involved in thymidine nucleotide biosynthesis.’


Early 20th century: from thymine + -ide + -ine.