One of the mysteries of the English language finally explained.
A synthetic compound derived from phenothiazine, used as a tranquilizer, chiefly in the treatment of mental illness.
- ‘Neurotoxicity has been reported when lithium is combined with haloperidol, thioridazine, chlorpromazine, and fluphenazine.’
- ‘The Irish Medicines Board has decided to ban the use of the antipsychotic drug thioridazine in children because of fears over cardiac side effects.’
- ‘Chlorpromazine, haloperidol and thioridazine became the standard treatments for schizophrenia.’
- ‘The phenothiazine associated with most deaths was not thioridazine but chlorpromazine.’
- ‘We compared the frequency of cardiac arrest and ventricular arrhythmia associated with different antipsychotic drugs, in particular comparing thioridazine to haloperidol.’
- ‘In some cases, patients who experience unacceptable rigidity, akathisia, or dystonia with high potency agents may benefit from a lower potency neuroleptic such as thiothixene or thioridazine.’
1950s: from thio- + ( pipe)rid(ine) + azine.
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