One of the mysteries of the English language finally explained.
(of organisms or cells) genetically similar or identical and hence immunologically compatible, especially so closely related that transplantation does not provoke an immune response.
- ‘The cells produced potent stimulation of allogenic T cells and syngeneic T cells specific for purified protein derivative in the absence of exogenous peptides.’
- ‘It was shown that spleen cells and infiltrating leukocytes isolated from well-functioning cardiac allografts in immunologically enhanced adult rats suppressed spontaneous blastogenesis of normal syngeneic cells in vitro.’
- ‘These findings were also observed in syngeneic animals (although less frequently), particularly in the first 3 days after surgery.’
- ‘Three syngeneic animals and one animal with allograft had marked focal uptake of annexin V in a linear pattern corresponding to the left thoracotomy site.’
- ‘Furthermore, we reported that a pharmacologic inhibitor of IDO, 1-methyl tryptophan, induced maternal rejection of allogeneic but not syngeneic murine fetuses.’
1960s: from syn- ‘together’ + Greek genea ‘race, stock’ + -ic.
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