Definition of sulfapyridine in US English:


(British sulphapyridine)


  • A sulfonamide antibiotic used to treat some forms of dermatitis.

    • ‘Because the patient reacted to balsalazide but not sulphasalazine the hypersensitivity reaction may have been to the whole drug rather than the sulphapyridine moiety alone.’
    • ‘Patients will experience prompt relief of lesions within one to two days of initializing treatment with dapsone or sulfapyridine.’
    • ‘Sulfapyridine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase.’
    • ‘Sulfasalazine consists of a 5 - ASA molecule bound to sulfapyridine.’
    • ‘Skin lesions in linear IgA dermatosis and chronic bullous disease of childhood respond rapidly when treated with dapsone or sulfapyridine.’