Definition of splenomegaly in English:


Pronunciation /ˌsplenəˈmeɡəlē//ˌsplēnəˈmeɡəlē/


  • Abnormal enlargement of the spleen.

    • ‘In infiltrative diseases or other causes of chronic splenomegaly (like cirrhosis, lymphoma, and sarcoid) the spleen is very firm, often approaching the hardness of the cirrhotic liver.’
    • ‘Two helpful tips the authors present are that lymphangitic streaking is often consistent with cutaneous infection, and that splenomegaly is rare in metastatic cancer.’
    • ‘When I see patients with chronic syndromes where they have splenomegaly and disease progression over time, I always consider sarcoidosis.’
    • ‘These include mononucleosis, leukemia, splenomegaly, Hodgkin's disease, AIDS and all the various types of anemias.’
    • ‘Physical examination revealed normal growth and vital signs, no icterus, lymphadenopathy, ascites, splenomegaly, or other systemic abnormal findings.’


Early 20th century: from splen- spleen + Greek megas, megal- great.