Which Joe gave his name to ‘sloppy joes’? We look at five interesting sandwiches and their lexical origins.
A steroid derivative that is an aldosterone antagonist, which promotes sodium excretion and is used in the treatment of certain types of edema and hypertension.
- ‘Recent research has shown that treatment with spironolactone improves mortality and hospital readmission rates.’
- ‘Pharmacologic agents used have included hydrochlorothiazide, spironolactone, furosemide, propranolol, or hydralazine.’
- ‘We restricted our analyses to loop diuretics, angiotensin converting enzyme inhibitors, blockers, spironolactone, and digoxin.’
- ‘About two years before this admission he had developed ascites, and treatment with salt restriction, spironolactone, and frusemide was started.’
- ‘For example, ACE inhibitors, beta-blockers, ARBs, spironolactone and digoxin are probably not necessary in all patients.’
1960s: from spiro- + lactone, with the insertion of -one.
Are you looking for a word for a foolish person? We explore twelve interesting words to describe the dunderheads in your life.
Before you run for the hills, let’s run through a list of ‘run’ expressions that are running through our minds.
The definitions of ‘buddy’ and ‘bro’ in the OED have recently been revised. We explore their history and increase in popularity.