Definition of spermatogonium in US English:


nounPlural spermatogonia

  • A cell produced at an early stage in the formation of spermatozoa, formed in the wall of a seminiferous tubule and giving rise by mitosis to spermatocytes.

    • ‘In severely degenerated tubules, only spermatogonia and Sertoli cells were observed, and pachytene spermatocytes sloughing into the lumen were observed.’
    • ‘Males are consequently exposed to new antigens when spermatogonia mature, and the immune activity involved in the male reproductive system may lead to autoimmunity.’
    • ‘In the testis, these cells are termed the spermatogonia.’
    • ‘A primary spermatogonium surrounded by a pair of cyst cells undergoes four mitotic divisions, forming a cyst of 16 primary spermatocytes.’
    • ‘The primitive germinal cells are the spermatogonia, which lie peripherally in the tubule wall, outside the barrier of Sertoli cell junctions.’


Late 19th century: from sperm + modern Latin gonium (from Greek gonos ‘offspring, seed’).