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1Abnormal hardening of body tissue.
- ‘A doctor may suspect aortic valve sclerosis on hearing a heart murmur with a stethoscope.’
- ‘In MS, myelin is lost in multiple areas, leaving scar tissue called sclerosis.’
- ‘The lymph node biopsy showed sclerosis surrounding cellular nodules that contained clusters of large atypical cells admixed with small lymphocytes and numerous eosinophils.’
- ‘A close-up reveals the alternating areas of sclerosis and retained hepatic parenchyma in this nutmeg liver.’
- ‘It exhibited squamous differentiation, sclerosis, and eosinophilia.’
- ‘Among this latter group, there were four patients with rheumatoid arthritis, five with systemic sclerosis, three with systemic lupus erythematosus, five with dermatomyositis, and four with mixed connective tissue disease.’
- ‘In other pathologic states, such as systemic sclerosis or diabetes, the tissue elastic properties may prove more relevant.’
- ‘Its expression in lung tissue has been widely described in systemic sclerosis, idiopathic pulmonary fibrosis and pulmonary sarcoidosis, and bleomycin-induced lung fibrosis.’
- ‘An association between connective tissue diseases, particularly systemic sclerosis, and gastric antral vascular ectasia has been noted.’
- ‘The goal of treatment in patients with secondary progressive multiple sclerosis is to prevent progressive worsening of the disease.’
- ‘The authors conclude that idiopathic pulmonary fibrosis associated with systemic sclerosis has the histopathologic pattern of nonspecific interstitial pneumonia, but that the histopathologic pattern does not predict prognosis.’
- ‘The obstructions are due in part to shortening of the mesentery from sclerosis and impairment of the enteric blood supply, which may result in further cicatrization, kinking and narrowing.’
- ‘The purpose of this study was to evaluate the efficacy, safety, and effect on quality of life of outpatient sclerosis using small-bore pigtail catheters.’
- ‘Amyotrophic lateral sclerosis is a progressive disease affecting both upper and lower motor neurons.’
- ‘Glomerular sclerosis, manifested by proteinuria, progresses as patients age.’
- ‘Around 16% of patients with sclerosis progress to stenosis in seven years.’
- ‘Other collagen diseases, such as progressive systemic sclerosis and systemic lupus erythematosus, are associated with increased incidence of pneumothorax.’
- ‘Amyotrophic lateral sclerosis is a common neurologic disease associated with an inexorable decline in muscle strength.’
- ‘A 67 year old woman with secondary progressive multiple sclerosis had a recurrence of right sided trigeminal neuralgia.’
2Excessive resistance to change.‘the challenge was to avoid institutional sclerosis’
- ‘In other words, this is a story not about institutional sclerosis, but about the necessarily contingent process of institutional change.’
Late Middle English (originally denoting a hard external tumor): via medieval Latin from Greek sklērōsis, from sklēroun harden.
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