Definition of sarcosine in US English:



  • A crystalline amino acid which occurs in the body as a product of the metabolism of creatine.

    Alternative name: N-methylglycine; chemical formula: CH₃NHCH₂COOH

    • ‘Among non-renal cells, mouse hybridoma cells grew better in hyperosmotic media when given betaine, sarcosine, or dimethylglycine; protection increased with higher methylation.’
    • ‘Elevated sarcosine indicates toxic exposures and/or folate deficiency.’
    • ‘Fifty microliters of sarcosine were added and the cells were incubated on ice for an additional 15 min.’
    • ‘Abalone ovaries were homogenized in a Waring blender in solution D (4 M guanidinium thiocyanate, 25 mM Na citrate [pH 7], 0.5% sarcosine, and 0.5 M ß-mercaptoethanol) as previously described.’
    • ‘However, the inhibition of 5 - ALA-ME uptake by sarcosine was marginal and not statistically significant.’


Mid 19th century: from Greek sarx, sark- ‘flesh’ + -ine.