Definition of sarcolemma in US English:



  • The fine transparent tubular sheath which envelops the fibers of skeletal muscles.

    • ‘EC coupling occurs at specialized regions where the intracellular sarcoplasmic reticulum forms junctions with the sarcolemma or, more frequently, with tubular invaginations of the sarcolemma known as transverse tubules.’
    • ‘The newborn larvae migrate from the host's blood vessels through the sarcolemma of striated muscle tissue, where they penetrate and encyst inside an individual muscle cell.’
    • ‘The usual position of skeletal muscle nuclei and the discovery of the sarcolemma is credited to Bowman.’
    • ‘Structural abnormalities included loss of lateral alignment of myofibrils, perturbation of myofibril anchorage to the sarcolemma, abnormal mitochondrial number and organization, and loss of nuclear shape and positioning.’
    • ‘Desmin and vinculin are functionally related proteins that are present in the membrane-associated dense bodies in the sarcolemma of the smooth muscle cells.’
    covering, cover, case, casing, envelope, sleeve, wrapper
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Mid 19th century: from Greek sarx, sark- ‘flesh’ + lemma ‘husk’.