Definition of sarcoidosis in US English:



  • A chronic disease of unknown cause characterized by the enlargement of lymph nodes in many parts of the body and the widespread appearance of granulomas derived from the reticuloendothelial system.

    • ‘It is often idiopathic in origin, but may be associated with multiple sclerosis, sarcoidosis, syphilis, Lyme disease, and ocular lymphoma.’
    • ‘The etiology of the systemic granulomatous disease sarcoidosis remains obscure.’
    • ‘Endoscopic procedures may be helpful in the diagnosis of disorders such as inflammatory bowel disease and sarcoidosis.’
    • ‘Amyloidosis and other infiltrative diseases, including sarcoidosis and haemochromatosis, can cause a restrictive syndrome.’
    • ‘Granuloma formation in sarcoidosis may be a stereotypical response to multiple infectious and noninfectious agents.’