Definition of restriction fragment length polymorphism in English:

restriction fragment length polymorphism

noun

Genetics
  • A variation in the length of restriction fragments produced by a given restriction enzyme in a sample of DNA. Such variation is used in forensic investigations and to map hereditary disease.

    • ‘Fingerprinting of M. tuberculosis exploits restriction fragment length polymorphism of chromosomal DNA.’
    • ‘From January 1999, the virus was detected and typed using a polymerase chain reaction method and restriction fragment length polymorphism.’
    • ‘The most commonly used method for detecting HFE mutations was restriction fragment length polymorphism.’
    • ‘Molecular strain typing by restriction fragment length polymorphism was performed using DNA probes for IS6110 8 and PGCR9 repetitive sequences.’
    • ‘The COL7A1 gene has been located on chromosome 3 through genetic linkage studies with restriction fragment length polymorphism.’