Definition of replicative in US English:



  • Relating to or involving the replication of genetic material or living organisms.

    • ‘In addition, recombination may lead to the acquisition of mutations that compensate for a loss in viral fitness or replicative capacity due to previous acquisition of resistance mutations.’
    • ‘Normal diploid human cells multiply for a finite number of generations and then enter a state of replicative senescence.’
    • ‘Regardless of these problems, viral vectors which are replicative defective like El, E3-deleted, replication-deficient recombinant adenoviruses, have been used extensively in immunotherapy.’
    • ‘A common attribute of many of these single-stranded RNA viruses is the creation of a short-lived replicative intermediate, double-stranded RNA during the process of intracellular replication.’
    • ‘Viruses basically clone themselves by various means, and due to replicative error reproduction, they have a high mutation rate.’