One of the mysteries of the English language finally explained.
A bitter crystalline compound present in cinchona bark, used as a tonic and formerly as an antimalarial drug.
An alkaloid; chemical formula: C₂₀H₂₄N₂O₂
- ‘The cinchona tree contains more than 20 alkaloids of which quinine and quinidine are the most important.’
- ‘Some people drink tonic water with quinine to get the drug without the prescription.’
- ‘One doctor told me to drink tonic water for its quinine, but it doesn't seem to help.’
- ‘He was treated with intravenous doxycycline in a dosage of 100 mg twice daily and oral quinine in a dosage of 650 mg twice daily for three days.’
- ‘Doctors treat malaria by using anti-malarial drugs, such as chloroquine or quinine.’
- ‘I was drinking large quantities of tonic water, which contains quinine, when this started.’
- ‘Other important alkaloids are caffeine, ricinine, and quinine.’
- ‘For many years the treatment of malaria in Africa has relied on chloroquine, sulfadoxine combined with pyrimethamine, and quinine, with the latter being used mainly to treat severe cases.’
- ‘The stereochemistry of quinine is formidable: it has four chiral centres, and thus 16 stereoisomers - of which only one is the natural ingredient of cinchona bark.’
- ‘Medical breakthroughs, including sulfa drugs, penicillin, and quinine, were also a consequence of the war.’
- ‘Whether artemisinins given by any route should be replacing quinine as the initial treatment of choice for severe malaria in Africa remains an open question.’
- ‘The patient was treated with quinine sulfate and tetracycline for 7 days.’
- ‘One of the gold standard therapies for a long time was a drug called quinine, and that was a medication that was used for prophylaxis against malaria.’
- ‘My doctor prescribed quinine, which for me is a sure-fire solution.’
- ‘The two most important groups of drugs for malaria treatment are still based on quinine or artemisinin.’
- ‘In 1820, the single chemical quinine was isolated from the bark.’
- ‘I believe at that time we were taking a variant of quinine called mepacrine, a little yellow pill which turned us a delicate shade of buttercup, and when we went on leave our friends and relatives thought we had jaundice.’
- ‘Her treatment was changed to intravenous quinine 600 mg every 12 hours, and she was transferred to the local intensive care unit.’
- ‘But quinine may not be the best antimalarial treatment.’
Early 19th century: from Spanish quina ‘cinchona bark’ (from Quechua kina ‘bark’) + -ine.
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