Definition of quinidine in US English:

quinidine

noun

Medicine
  • A compound obtained from cinchona bark and used to treat irregularities of heart rhythm. It is an isomer of quinine.

    • ‘Intestinal absorption of penicillin, captopril, ciprofloxacin, quinidine and zidovudine was reported to be reduced when given with food.’
    • ‘Sinus node dysfunction is usually caused by drugs such as digoxin, quinidine, or procainamide.’
    • ‘This has been shown to occur with penicillin, valproic acid, quinidine, sulfonamides, cimetidine and heparin.’
    • ‘Metformin also may interact with medications such as cimetidine, digoxin, amiloride, quinidine, vancomycin, and trimethoprim, and may interfere with vitamin B12 absorption.’
    • ‘Treatment choices are to change the rhythm back to normal and maintain it with medications such as digitalis, quinidine, or other medicines or by electrical stunning of the heart (cardioversion).’

Origin

Mid 19th century: from Spanish quina ‘cinchona bark’ (from Quechua kina ‘bark’) + -ide + -ine.

Pronunciation

quinidine

/ˈkwinəˌdēn//ˈkwɪnəˌdin/