Definition of quinacrine in US English:



  • 1A synthetic compound derived from acridine, used as an anthelmintic and antimalarial drug.

    • ‘The drugs are quinacrine, used to treat malaria and the tropical parasite infection giardiasis, and chlorpromazine, which is given to patients with schizophrenia and other psychotic conditions.’
    • ‘If standard therapeutic regimens fail because of immunodeficiency or other issues, combinations of metronidazole and quinacrine can be administered for three weeks.’
    • ‘Hydroxychloroquine is the most widely used; its effectiveness was studied in combination with quinacrine, another antimalarial drug.’
    • ‘The Medical Research Council, which will oversee the trials, said national guidelines for studies of the antimalarial drug quinacrine will probably be agreed next month.’
    1. 1.1Biochemistry A nitrogen mustard derived from this, used as a fluorescent stain for chromosomes.
      • ‘First, cytogenetic techniques, especially quinacrine staining, were developed, enabling each chromosome to be recognized by its unique banding pattern.’


1930s: blend of quinine and acridine.