A synthetic compound derived from pyrimidine, used to treat malaria.
- ‘Small colony mutants 540 and a subclone of 540 were obtained from cells exposed to pyrimethamine.’
- ‘Induced cross resistance to other drugs, like sulfadoxine and pyrimethamine, an antimalarial treatment, is a major concern.’
- ‘Prophylaxis with trimethoprim-sulfamethoxazole or dapsone plus pyrimethamine is recommended.’
- ‘A case report suggests carnitine deficiency was induced in a patient receiving sulfadiazine and pyrimethamine.’