Definition of proteasome in US English:



  • A protein complex in cells containing proteases; it breaks down proteins that have been tagged by ubiquitin.

    • ‘Among the archaebacterial-specific genes several ribosomal proteins, DNA metabolic enzymes, and proteasome subunits are prominent.’
    • ‘The scientists will now focus on better understanding the precise mechanism by which ubiquitin and the proteasome regulate viral budding and maturation.’
    • ‘This suggests that independent protein degradation pathways for ubiquitin, as well as for the proteasome complex, may exist in strawberry fruit.’
    • ‘In the context of the cell, the unfolding process participates in several important steps in cellular physiology, such as protein turnover in proteasomes.’
    • ‘The proteasome and other endoproteolytic enzymes are located in the cytosol and may also be involved in the catabolism of larger fragments.’


1980s: from protein + -some.