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A compound of the prostaglandin type produced in arterial walls, which functions as an anticoagulant and vasodilator.
- ‘Prostaglandins, especially prostacyclin, are secreted in all veins and have a distinct antiplatelet-aggregating property.’
- ‘Aspirin also reduces endothelial cell production of prostacyclin, an inhibitor of platelet aggregation and a vasodilator.’
- ‘Other common therapies including anticoagulant treatment and prostacyclin have been used.’
- ‘The endothelium produces several regulatory mediators, including nitric oxide and prostacyclin, which are vasodilators, and endothelin, which is a vasoconstrictor.’
- ‘Thromboxane is regulated by prostacyclin released from injured epithelial cells through negative feedback.’
1970s: from prostaglandin + cyclic + -in.
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