Definition of progestin in US English:



  • A natural or synthetic steroid hormone, such as progesterone, that maintains pregnancy and prevents further ovulation during pregnancy.

    • ‘It is well known that gonadal steroids such as progestins, androgens and estrogens are produced by the ovary under the influence of gonadotropins.’
    • ‘He had developed a pill, containing synthetically produced versions of the hormones oestrogen and progestin, which would suppress ovulation apparently without side-effects.’
    • ‘Reported androgenic effects of synthetic progestins include fluid retention, reduction of HDL cholesterol levels, headaches and mood disturbance.’
    • ‘HRT is made up of two types of hormones, oestrogens and progestins, or synthetic progesterone.’
    • ‘Women in both groups will also wear a patch that delivers estrogen and take tablets containing the hormone progestin.’


1930s: from pro- + gestation + -in.