Definition of progenote in US English:

progenote

noun

Biology
  • A hypothetical simple biological entity or organized system of a kind that could have included the evolutionary common ancestor of eukaryotes and prokaryotes.

Origin

1970s. From pro- + geno- + -ote.

Pronunciation

progenote

/prə(ʊ)ˈdʒiːnəʊt/