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Relating to or denoting substances that promote the conversion in the blood of the inactive protein prothrombin to the clotting enzyme thrombin.
- ‘The cap acts as a protective barrier between circulating blood and the thrombogenic, procoagulant contents of the lesion.’
- ‘In hemostasis, there is a balance between procoagulant factors and natural anticoagulant proteins.’
- ‘Thrombomodulin is an integral membrane glycoprotein that binds thrombin changing it from a procoagulant protein to an anticoagulant.’
- ‘Hemostasis involves the integration of many procoagulant proteins, natural anticoagulants, fibrinolytic proteins, and platelet surface glycoproteins.’
- ‘Protective mechanisms prevent thrombin and other procoagulant enzymes from forming in healthy intact blood vessels.’
A procoagulant substance.
- ‘This phenomenon is attributed to platelet-aggregating factors and procoagulants from the tumor or its necrotic products.’
- ‘The exudate, procoagulants, and leukocytes form casts in the airways, resulting in poor gas exchange.’
- ‘Chemotherapy acts by killing leukemic cells, which release procoagulants that can produce disseminated intravascular coagulation.’
- ‘When nitric oxide is deficient or used inadequately, endothelium becomes a procoagulant instead of an anticoagulant, and vasoactive molecules, cytokines, and growth factors are formed.’
- ‘Taipan venom is overwhelmingly neurotoxic, including pre and post-synaptic neurotoxins, as well as powerful procoagulants and myolysins.’
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