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A synthetic compound derived from quinoline, used in the treatment of malaria.
- ‘Chemoprophylaxis may soon be advanced if Malarone, primaquine, or Tafenaquine (a new 8-aminoquinoline) become licensed for this indication.’
- ‘Several other drugs have been evaluated, including tetracycline, primaquine, sulfadiazine and pyrimethamine (Fansidar).’
- ‘Fifteen years ago, surveys done by the Ministry of Health found that most people on the island nation carry an enzyme that renders primaquine, a common anti-malarial drug, useless.’
- ‘The authors also discuss the use of primaquine and other 8-aminoquinoline compounds that are being investigated for malarial prophylaxis in resistant areas.’
- ‘To prevent relapses, a course of primaquine may be given as terminal prophylaxis at the conclusion of the standard post-travel chemoprophylaxis regimen.’
1940s: apparently from Latin prima (feminine of primus ‘first’) + quin(olin)e.
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