Definition of potentiate in US English:



[with object]technical
  • Increase the power, effect, or likelihood of (something, especially a drug or physiological reaction)

    ‘the glucose will potentiate intestinal absorption of sodium’
    • ‘Ginseng can interact with antihypertensives, and Siberian ‘ginseng’ can potentiate the effects of digoxin.’
    • ‘It appears that both the antiplatelet aggregation activity as well as the analgesic action of aspirin 22 potentiates the effect of pentoxifylline.’
    • ‘Glycyrrhizin may potentiate the effects of corticosteroids, antihypertensive agents, diuretics, and hormones.’
    • ‘One drug does not therefore potentiate the adverse effects of another.’
    • ‘Alternatively, devising agents to slow the breakdown of natural cannabinoids might potentiate their analgesic effects.’
    • ‘Because it appears to potentiate gamma-aminobutyric acid inhibitory neurotransmitters, it may potentiate anesthesia's sedative effects.’


Early 19th century: from potent, on the pattern of substantiate.