Definition of polypharmacal in US English:

polypharmacal

adjective

Medicine
  • = polypharmaceuticalrare.

Origin

Mid 17th century (in an earlier sense). From ancient Greek πολυϕάρμακος knowing many drugs or charms, in Hellenistic Greek also given to the use of drugs or medicines, compounded of many drugs, (of countries) abounding in healing or poisonous herbs (from πολυ- + ϕάρμακον medicine: see pharmaco-) + -al.

Pronunciation

polypharmacal

/ˌpɒlɪˈfɑːməkl/