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A linear organic polymer consisting of a large number of amino-acid residues bonded together in a chain, forming part of (or the whole of) a protein molecule.
- ‘It is a basic protein with a single polypeptide chain and acts on cellular and model lipid membranes.’
- ‘They both develop random transient beta-strands across the whole polypeptide chain.’
- ‘These enzymes break down proteins into polypeptides and then into amino acids, which are absorbed through the gut wall into the bloodstream.’
- ‘Unlike larger polypeptides and proteins, small nucleic acid duplexes and hairpins do not have a dense core to which this effect would apply.’
- ‘The LDL receptor is a polypeptide of 839 amino acids that spans the plasma membrane.’
Early 20th century: from poly- many + peptone + -ide.
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The definitions of ‘buddy’ and ‘bro’ in the OED have recently been revised. We explore their history and increase in popularity.