Definition of platelet-derived growth factor in US English:

platelet-derived growth factor


  • A cytokine composed of two homologous polypeptide chains, produced by platelets, endothelial cells, fibroblasts, and various other types of cell, and having the main function of stimulating the division of mesenchymal cells and promoting wound healing (abbreviated PDGF).


1970s; earliest use found in Proceedings of the National Academy of Sciences of the United States of America.