Definition of plasminogen in US English:



  • The inactive precursor of the enzyme plasmin, present in blood.

    • ‘This is performed largely by the enzyme plasmin, generated from its inactive precursor, plasminogen.’
    • ‘Within the fibrinolytic system, plasmin is generated from plasminogen by tissue plasminogen activator, which upon activation lyses fibrin clots.’
    • ‘The Borrelia need plasminogen from human blood to migrate to the tick's salivary glands and then infect the human.’
    • ‘It produces an antifibrinolytic effect through the reversible blockade of lysine binding sites on plasminogen molecules.’
    • ‘Tissue plasminogen activator and, to a lesser degree, urokinase are serine proteases which convert plasminogen to plasmin.’