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An enzyme, formed in the blood in some circumstances, that destroys blood clots by attacking fibrin.
- ‘The fibrinolytic system involves a series of enzymatic reactions that results in the conversion of the proenzyme, plasminogen, into the trypsin-like lyric enzyme, plasmin.’
- ‘The broad spectrum serine protease plasmin is formed following cleavage of the zymogen precursor plasminogen by host activators tissue plasminogen activator and urokinase.’
- ‘Plasminogen activators attached to fibrin activate plasminogen, causing the release of the enzyme plasmin within clots and thrombi.’
- ‘Degradation of fibrin clots is the function of plasmin, a serine protease that circulates as the inactive proenzyme, plasminogen.’
- ‘Substitution of Glu 351 also altered the specificity toward non-cognate proteases: plasmin and thrombin.’
Mid 19th century: from French plasmine, from late Latin plasma mold, image.
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