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A synthetic compound used as an analgesic drug, especially in the treatment of horses.
- ‘Many horses receive phenylbutazone on a daily basis for weeks, months, or even years, potentially contributing to increased intestinal permeability.’
- ‘In other studies, excessive doses of phenylbutazone have been shown to induce a range of adverse effects within a relatively short period of time, including gastric ulcers, colitis and kidney damage.’
- ‘Dogs with panosteitis usually respond to analgesics such as aspirin or phenylbutazone.’
- ‘In addition, previous experimental work by Vogel indicates that acetylsalicylic acid, indomethacin, and phenylbutazone strengthen uninjured collagenous structures in rats.’
- ‘While gastric ulcers in horses are common, their presence may be due in part to the use of phenylbutazone.’
1950s: from phenyl + but(yl) + azo- + -one.
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