Definition of phenylbutazone in US English:



  • A synthetic compound used as an analgesic drug, especially in the treatment of horses.

    • ‘Dogs with panosteitis usually respond to analgesics such as aspirin or phenylbutazone.’
    • ‘In other studies, excessive doses of phenylbutazone have been shown to induce a range of adverse effects within a relatively short period of time, including gastric ulcers, colitis and kidney damage.’
    • ‘In addition, previous experimental work by Vogel indicates that acetylsalicylic acid, indomethacin, and phenylbutazone strengthen uninjured collagenous structures in rats.’
    • ‘Many horses receive phenylbutazone on a daily basis for weeks, months, or even years, potentially contributing to increased intestinal permeability.’
    • ‘While gastric ulcers in horses are common, their presence may be due in part to the use of phenylbutazone.’


1950s: from phenyl + but(yl) + azo- + -one.