One of the mysteries of the English language finally explained.
A synthetic compound used as a vasodilator, especially in certain cases of hypertension.
- ‘The effectiveness of phentolamine can be seen immediately with a dramatic change in local skin color and temperature.’
- ‘Epinephrine may interact with alpha- and beta-adrenergic blocking agents such as propranolol and phentolamine.’
- ‘Agitation and anxiety can be controlled with benzodiazepines, and hypertension with labetalol, phentolamine, or nitroprusside.’
- ‘Severe hypertension can be treated with labetalol, phentolamine, nitroprusside, or similar agents.’
- ‘Tachycardia, prolonged hypotension, cardiac arrhythmias, weakness, dizziness, flushing, orthostatic hypotension, nausea, vomiting, and diarrhea are potential side effects of IV phentolamine.’
1950s: from phen- + tol(yl) (an isomeric cyclic radical derived from toluene) + amine.
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