Definition of phenothiazine in US English:



  • 1A synthetic compound which is used in veterinary medicine to treat parasitic infestations of animals.

    A heterocyclic compound; chemical formula: C₁₂H₉NS

    1. 1.1Psychiatry Any of a group of derivatives of phenothiazine with tranquilizing properties, used as tranquilizers in the treatment of mental illness.
      • ‘However, the data presented suggest that some photosensitizing effect in humans is possible, although lower than that exerted by other drugs such as quinolone antibiotics, anti-inflammatory drugs or phenothiazines.’
      • ‘Medications with antihistamine properties, such as anticholinergic agents, phenothiazine, and tricyclic antidepressants, also should be discontinued before skin testing.’
      • ‘Many prescription medications, including digitalis, phenothiazine, theophylline, and beta agonists, can cause palpitations.’
      • ‘The systemic use of phenothiazines, a class of neuroleptic drugs used in the therapy of mental disorders, such as schizophrenia, organic psychoses and other mental disorders, is known to induce photosensitization of the skin.’
      • ‘The finding that phenothiazines reduce the incidence of cancer in humans generated a broad range of experimental studies, which confirmed their antitumor, cancer-chemopreventive and antimutagenic activities.’