Definition of perfuse in US English:



[with object]
  • 1Permeate or suffuse (something) with a liquid, color, quality, etc.

    ‘Glaser perfused the yellow light with white’
    figurative ‘such expression is perfused by rhetoric’
    • ‘The streets of this city are like pipes from a toilet, perfused by the stench of waste!’
    • ‘The community was perfused with creative release, a celebration enfusing Brit Pop, Cool Britannia and renewed exploration of the human spirit.’
    • ‘At 10 minutes, lungs were perfused with physiologic saline through the pulmonary artery.’
    • ‘Segments were perfused with filtered water which was not acidified.’
    • ‘When the Reformers rediscovered the Bible, they rediscovered a two-tier Holy Land: a real, dusty place and, lying over it and perfusing it, an even more real spiritual land.’
    pervade, spread through, fill, filter through, diffuse through, imbue, penetrate, pass through, percolate through, extend throughout, be disseminated through, flow through, charge, suffuse, run through, steep, impregnate, inform, infiltrate
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    1. 1.1Medicine Supply (an organ or tissue) with a fluid, typically treated blood or a blood substitute, by circulating it through blood vessels or other natural channels.
      ‘the transplanted kidney is perfused at low pressure by retrograde flow’
      ‘the isolated perfused rat liver’
      • ‘Heart failure is the deterioration of the heart's ability to pump blood throughout the body and adequately perfuse the major organs.’
      • ‘The pressure required to traverse an arterial stenosis and perfuse the distal tissues of the foot may not be met.’
      • ‘This effect is generally not accepted to be an improvement in the diseased segment of blood vessel, but the formation of collateral vessels perfusing the ischaemic tissue.’
      • ‘In a later more detailed study, the blood pressure perfusing the lungs of healthy subjects proved to be quite low, only about one-fifth of the normal systemic arterial blood pressure.’
      • ‘To determine the effect of protecting leukocytes from hyperosmolar exposure, we perfused lungs with leukocyte-free blood for 15 min.’


Late Middle English (in the sense ‘cause to flow through or away’): from Latin perfus- ‘poured through’, from the verb perfundere, from per- ‘through’ + fundere ‘pour’.