Definition of pepsinogen in English:

pepsinogen

noun

Biochemistry
  • A substance which is secreted by the stomach wall and converted into the enzyme pepsin by gastric acid.

    • ‘Examples of important proenzymes include pepsinogen, trypsinogen and chymotrypsinogen, which give rise to the proteolytic digestive enzymes.’
    • ‘In the stomach, pepsinogen is secreted, and activated into pepsin by the acid that is secreted at the same site.’
    • ‘Ginger is an excellent natural antacid because it prevents the breakdown of pepsinogen to pepsin: the latter irritates tissue to cause peptic ulcers.’
    • ‘This process is autocatalytic for some pro-enzymes such as pepsinogen [23-25] and cathepsins D and E.’
    • ‘The sensitivity of the assay is not great enough to detect the small quantity of pepsinogen known to be present in blood (presumably after direct absorption from gastric mucosal cells).’

Pronunciation

pepsinogen

/pepˈsinəjen/