Definition of pentamidine in English:

pentamidine

noun

Medicine
  • A synthetic antibiotic drug used chiefly in the treatment of pneumocystis carinii pneumonia (PCP) infection.

    • ‘The growing problem of drug resistance to pentamidine and melarsoprol has driven clinicians to consider combination chemotherapy regimens.’
    • ‘For patients that cannot tolerate any of these drugs, weekly inhaled pentamidine is used.’
    • ‘Aerosolized pentamidine and dapsone are believed to be safe during pregnancy; however, pyrimethamine should be used with caution.’
    • ‘Sodium antimony gluconate and pentamidine have been used as the first and second line drugs respectively.’
    • ‘Dapsone and inhaled pentamidine are commonly employed alternatives to trimethoprim-sulfamethoxasole, but appear to be somewhat less effective in preventing PCP.’

Origin

1940s: from pentane + amide + -ine.

Pronunciation:

pentamidine

/penˈtaməˌdēn/