Definition of out of one's skull in US English:

out of one's skull

phrase

informal
  • 1Out of one's mind; crazy.

    • ‘I think you're out of your skull for coming back.’
    • ‘When Rhi moved in I was very ill, depressed out of my skull, afraid of the world and generally an apathetic blob.’
    • ‘Anyone who seriously thought Lord Of The Rings was going to win the top honours is out of their skull.’
    • ‘‘I knew I would go out of my skull if I didn't work,’ she says.’
  • 2Very drunk.

    • ‘Emil's drunk out of his skull and Lexi's scared to death.’
    • ‘I was bored out of my skull listening to about two and a half hours of the above.’
    • ‘I hope Elvis was wasted out of his skull and bought it as a joke, but that's wishful thinking.’
    • ‘‘He was clearly out of his skull on drugs,’ he said.’
    • ‘I'm in Canada, and drunk out of my skull, mind you, so ignore me. / / thread rot…’
    • ‘She's the responsible one, even when she's hammered out of her skull.’
    • ‘People can feel there is nothing to identify with but David Beckham, and all that's left is to get out of your skull on drugs and alcohol.’
    intoxicated, inebriated, drunken, befuddled, incapable, tipsy, the worse for drink, under the influence, maudlin
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