Definition of ototoxic in English:

ototoxic

adjective

Medicine
  • Having a toxic effect on the ear or its nerve supply.

    • ‘These medications must be administered carefully in patients who are elderly, have poor renal function, require a prolonged course of medication, or require simultaneous administration of multiple ototoxic agents.’
    • ‘Exposure to solvents alone significantly increased the risk for hearing loss, most likely the result of ototoxic effects along the auditory pathway.’
    • ‘Simultaneous administration of several ototoxic agents or prolonged treatment with high dosages of an ototoxic medication should be avoided when possible.’
    • ‘Leading causes of acquired hearing loss include infectious diseases, especially meningitis and otitis media, trauma to the nervous system, damaging noise levels, and ototoxic drugs.’
    • ‘It is assumed that people with dark eyes also have more melanin in the inner ear than those with light eyes, and melanin causes the retention of ototoxic derivatives within the cochlea.’

Pronunciation

ototoxic

/ˌōdəˈtäksik/