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An inherited disorder characterized by extreme fragility of the bones.
- ‘Three children with severe osteogenesis imperfecta received allogeneic bone marrow transplants; in two osteoblast engraftment was shown.’
- ‘Kwanini, who suffers from osteogenesis imperfecta (brittle bone disease), has been in a wheelchair since the age of nine.’
- ‘For example, children with an inherited condition known as osteogenesis imperfecta have bones that are brittle and more susceptible to breaking.’
- ‘Various clinical conditions such as osteomalacia, osteoporosis, and osteogenesis imperfecta bear witness to the inadequacies of poorly formed bone in fulfilling the role of support to the human body.’
- ‘In a recent study in Nature Medicine, normal bone marrow derived cells that were infused into patients suffering from osteogenesis imperfecta, a genetic disease.’
Modern Latin, from osteogenesis + Latin imperfecta ‘imperfect’ (feminine of imperfectus).
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