Definition of osteoclast in English:

osteoclast

noun

Physiology
  • A large multinucleate bone cell which absorbs bone tissue during growth and healing.

    • ‘Vitamin D indirectly stimulates osteoclasts to resorb bone and is necessary for the intestinal absorption of calcium.’
    • ‘Williams also showed that genistein decreased acid secretion by osteoclasts, thus decreasing bone dissolution.’
    • ‘Note the presence of numerous osteoclasts lining the bone trabeculae.’
    • ‘They activate mature osteoclasts indirectly through osteoblasts, inhibit osteoclast cell death, and stimulate osteoclast progenitor formation.’
    • ‘The rate at which cells called osteoclasts break down bone is slowed, and the production of new bone increases.’

Origin

Late 19th century: from osteo- ‘bone’ + Greek klastēs ‘breaker’.

Pronunciation

osteoclast

/ˈɑstiəˌklæst//ˈästēəˌklast/