Definition of nucleoplasm in US English:



  • The substance of a cell nucleus, especially that not forming part of a nucleolus.

    • ‘However, thermodynamic driving forces may indeed arise in experiments, as the result of chemical potential and/or concentration gradients between the cytoplasm and the nucleoplasm.’
    • ‘Cells are partially fixed, lysed, and then extensively washed such that all cytoplasm and nucleoplasm are removed.’
    • ‘In this paper we describe the tracking of single proteins in the cytoplasm and nucleoplasm of mammalian cells.’
    • ‘Indeed, RpL5 has been shown to specifically bind 5S rRNA and transport it from the nucleoplasm to the nucleolus for assembly into the 60S ribosomal subunit.’
    • ‘In young animals, the cytoplasm and nucleoplasm of most cells was smooth and uniform.’