Definition of nodule in US English:

nodule

noun

  • 1A small swelling or aggregation of cells in the body, especially an abnormal one.

    • ‘Leprosy is associated with symmetric skin lesions, nodules, plaques, and a thickened dermis.’
    • ‘A computed tomography scan showed multiple nodules in the liver and bilateral pulmonary metastasis.’
    • ‘These papules or nodules develop in areas that the patient can reach.’
    • ‘The clinical significance of these small nodules of Langerhans cells is not fully understood.’
    • ‘The subcutaneous nodule, 1.7 cm across, was excised under local anaesthetic.’
    • ‘Her wrist and knee were warm, red, swollen, and tender, but she had no rashes or subcutaneous nodules.’
    • ‘She already had hepatic involvement, and the subcutaneous nodules spread over the whole of her trunk.’
    • ‘Endoscopy evaluation revealed an antral nodule, which was biopsied.’
    • ‘Metastases from cutaneous melanoma normally present as flesh coloured papules or nodules in the skin.’
    • ‘Regional adenopathy, satellite lesions, and subcutaneous nodules can be present.’
    • ‘This is seen in longstanding sarcoidosis, in which asymptomatic, violaceous nodules are seen on nose, fingers, and ears.’
    • ‘Ultrasound techniques classify nodules as solid or cystic in the belief that solid lesions might be malignant and cystic lesions benign.’
    • ‘The most severe form of leprosy produces large disfiguring nodules, or lumps.’
    • ‘A thyroid nodule is a palpable swelling in a thyroid gland with an otherwise normal appearance.’
    • ‘Computed tomography showed a solitary nodule in the right lobe of the liver.’
    • ‘This produces a deeper infection, in the form of pustules and nodules.’
    • ‘Rashes with purpura, urticaria, and subcutaneous nodules are common.’
    • ‘Except for her purulent, multifocal, subcutaneous nodules, she was generally in good health.’
    • ‘The most common presentation for thyroid or salivary gland cancer is an asymptomatic nodule within the gland.’
    • ‘The most common presenting lesions are papules, vesicles, pustules, and nodules.’
    • ‘It tends to appear as a papule or nodule with an epithelialized, pearly appearance, but may ulcerate in some cases.’
    growth, lump, swelling, protuberance, protrusion, knob, outgrowth
    View synonyms
    1. 1.1 A swelling on a root of a leguminous plant, containing nitrogen-fixing bacteria.
      • ‘From this point on, the bacteria and the plant - members of two separate kingdoms - share the know-how and labor needed to construct what is essentially a new organ: a fully operational nitrogen-fixing root nodule.’
      • ‘This interaction culminates in the formation of root nodules and in the differentiation of bacteria into bacteroids, which are capable of reducing atmospheric nitrogen into ammonia.’
      • ‘In return, the plant shelters and nourishes the bacterium inside root nodules, where nitrogen fixation occurs.’
      • ‘Nitrogen-fixing bacteria in the root nodules of leguminous plants (such as peas and clover) take in nitrogen direct from the air and pass it on to the plant, both feeding the plant and enriching the soil.’
      • ‘Rhizobial bacteria generally enter roots of legumes via root-hairs and induce the formation of root nodules.’
  • 2A small rounded lump of matter distinct from its surroundings, for example, of flint in chalk, carbon in cast iron, or a mineral on the seabed.

    • ‘Others contain cores of malachite that constitute up to about 30 percent of the nodule.’
    • ‘This type of digging yielded hundreds of nodules for area collectors and rock shops.’
    • ‘The minute copper particles are concentrated in bands or zones in the center of the nodules as well as near the edges.’
    • ‘Individual nodules range from a fraction of an inch to more than 14 inches across.’
    • ‘In recent years more of these nodules have been collected from the mine dump and a drift in the mine.’
    • ‘It is more visible when there are beds rich in clays, shell layers, or flints nodules.’
    • ‘It has been estimated by some collectors that tons of the nodules were recovered from this dump.’
    • ‘Many of the nodules contain copper inclusions and, rarely, silver inclusions.’
    • ‘The most persistent bed of nodules is found in the Late Devonian Huron Shale.’
    • ‘Crystals of brown sphalerite are found in fractures and on the surfaces of some chert nodules.’
    • ‘The sediment was cemented with iron carbonate to form a hard nodule distinct from the shale around it.’
    • ‘Many of the early datolite nodules recovered were dark purple with a distinctive black rind.’
    • ‘Turquoise here was found as vein fillings and nodules in weathered Precambrian granite.’
    • ‘Once dry, the individual nodules are immersed in water, causing much of the clay to fall away.’
    • ‘Historically, similar nodules were collected from the upper levels of the Centennial mine.’
    • ‘The most highly prized datolites have concentrated copper inclusions near the center of the nodule and are pinkish-gray in color.’
    • ‘On a second trip to the same area, additional nodules were recovered that exhibited the same dull colors.’
    • ‘A few people still poke around what is left of the mine dumps, but a datolite nodule is rarely found.’
    • ‘In these steep underwater cliff areas were chimneys of gravel that contained datolite nodules.’
    • ‘Pyritic nodules, up to 1 cm in diameter, with internal radial structure, are abundant in the claystones.’
    lump, bump, protuberance, projection, protrusion, bulge, swelling, knot, node, gnarl, growth, outgrowth, excrescence, carbuncle, tumour
    View synonyms

Origin

Late Middle English: from Latin nodulus, diminutive of nodus ‘knot’.

Pronunciation

nodule

/ˈnäjo͞ol//ˈnɑdʒul/