Definition of neurofibroma in US English:



  • A tumor formed on a nerve cell sheath, frequently symptomless but occasionally malignant.

    • ‘A number of examples of tumors with some malignant features exist, for example, oyster epithelioma, neurofibromas, sarcomas, and leukocytic neoplasms (leukemia-like disorders).’
    • ‘Benign tumors called neurofibromas are found on or under the skin or along the nerves of the body.’
    • ‘The intracranial tumors associated with neurofibromatosis include optic gliomas, other astrocytomas, neurilemomas, acoustic neuromas, neurofibromas, and meningiomas.’
    • ‘Development of benign neurofibromas versus malignant neurofibrosarcomas may be the difference between inactivation of one NF1 allele versus both alleles, respectively.’
    • ‘In fact, pain or sudden enlargement of a pre-existing mass in this setting should lead to immediate biopsy to exclude the possibility of malignant transformation of a neurofibroma.’