Definition of nephrotoxic in US English:

nephrotoxic

adjective

  • Damaging or destructive to the kidneys.

    • ‘Synergistic toxicity is generally thought to occur when concomitant nephrotoxic drugs are used.’
    • ‘Critical measures include maintaining adequate intravascular volume and mean arterial pressure, discontinuing all nephrotoxic drugs, and eliminating exposure to any other nephrotoxins.’
    • ‘Patients treated with nephrotoxic medications are at greater risk of developing renal failure.’
    • ‘Several other drugs used in CF care have nephrotoxic and ototoxic potential.’
    • ‘The common potentially reversible causes are sepsis, excessive diuresis or paracentesis, and nephrotoxic drugs.’

Pronunciation

nephrotoxic

/ˌnefrəˈtäksik/