Definition of necrosis in US English:



  • The death of most or all of the cells in an organ or tissue due to disease, injury, or failure of the blood supply.

    • ‘Complications of radiation therapy include anal ulcers, anal stenosis and necrosis.’
    • ‘As the disease progresses, necrosis and liver cell death may lead to fibrosis.’
    • ‘The present work presents a mechanism leading to cell death, necrosis at the tissue level.’
    • ‘The combination increases the risk of soft tissue necrosis and osteonecrosis.’
    • ‘The pathogenesis of necrosis in toxoplasma encephalitis is unclear.’
    • ‘Small polyvinyl alcohol beads obstruct the blood supply to the fibroids, causing necrosis and shrinkage’
    • ‘Centrally within the larger foci of squamous metaplasia, necrosis may be seen.’
    • ‘The sinusoidal pattern may have been due to sepsis or necrosis in adjacent tissues.’
    • ‘Multifocal calcifications associated with tumor cell necrosis were also seen.’
    • ‘Liver cell necrosis is indicated by highly elevated serum liver transaminase levels.’


Mid 17th century: modern Latin, from Greek nekrōsis (see necro-, -osis).