Gradual degeneration and death of cells in the body tissues.
- ‘Ulceration occurs in about one third of diabetic patients with necrobiosis lipoidica, and spontaneous remission is relatively uncommon.’
- ‘There are multiple other reports of silk suture-induced foreign-body reactions causing significant necrobiosis.’
- ‘Apart from necrobiosis lipoidica, diabetes is not a primary cause of ulceration but often leads to ulceration through neuropathy or ischaemia, or both.’
- ‘Diabetic necrobiosis typically causes discrete pretibial plaques, not the confluent skin changes seen in this patient.’
- ‘Three common skin disorders seen in patients with diabetes are diabetic dermopathy, necrobiosis lipoidica diabeticorum, and bullous diabeticorum.’