Definition of naloxone in English:

naloxone

noun

Medicine
  • A synthetic drug, similar to morphine, that blocks opiate receptors in the nervous system.

    • ‘Moreover, several studies reported that precipitating withdrawal in opiate-dependent animals by an injection of the opiate antagonist, naloxone, increases morphine self-administration.’
    • ‘She was given intravenous naloxone for suspected opiate induced hypoventilation, but her condition was unchanged.’
    • ‘Antagonist drugs such as naloxone can block the actions of opioid agonists.’
    • ‘In these patients, itch can be debilitating, and treatment with opioid antagonists such as naloxone or naltrexone is recommended.’
    • ‘Drugs such as the opioid antagonist naloxone and the benzodiazepine antagonist flumazenil may be used to counter the respiratory depressive effects of these drugs.’

Origin

1960s: contraction of N-allylnoroxymorphone.

Pronunciation:

naloxone

/nəˈläksōn/